Reading up on Domino’s shopping guides is like having your own personal product concierge. We do the tedious part—deep-dive research, hands-on testing, and tapping experts for advice—so all you have to do is hit “add to cart.” That’s why we call them Simply the Best.

We’ll be the first to admit that shopping for a waterproof mattress protector isn’t the most glamorous task—but after finding the bed of your dreams, let’s just say it’s a must. Think of it as insurance against kids bopping about with sippy cups, puppy drool, or cozying up to a full cup of coffee still in your robe—a spill is inevitable. Sure, sheets can be washed, but once a mattress is saturated and soiled, it’s hard to get a stain out. According to bedding brand Coop Home Goods, moisture is a mattress’s number-one enemy, so even if you’re not accident-prone, child-free, or have no pets, there’s still humidity, perspiration, and mildew to factor in. The best waterproof mattress protectors, handpicked by Domino editors, prioritize brands we love, high-quality materials, and effectiveness—so go on, have that second mimosa in bed.

Our Favorites

Best Overall: Casper Waterproof Mattress Protector 

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Cover material: Polyester, thermoplastic polyurethane, spandex | Closure: Slip-on | Hypoallergenic: yes | Breathable: yes | Sizes: Fits mattresses up to 16 inches deep

What we like:

  • 30-day trial
  • Cling-stretch design so it stays put
  • 1-year warranty

Worth noting:

  • Synthetic materials 

Why we chose it: Consistently touted the best of the best, overall. 

One of the O.G. modern bed-in-a-box brands, Casper is consistently ranked as one of the best waterproof mattress protector brands, too. Just like the mattress, you can check it out firsthand for 30 days before you commit. This protector’s clinging stretch design ensures that after you slip it on, it won’t shift or pop off in the middle of the night; it’s also constructed to be breathable with microscopic pores incorporated throughout. And deep mattresses are welcome here—it fits any up to 16 inches deep. For those who toss and turn, you’ll also be happy to know that it’s crafted from “quiet materials” that should be crinkle-free, so your precious shut-eye won’t be interrupted. 

Best Value: Coop Ultra Luxe Waterproof Mattress Protector 

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Cover material: Polyester and rayon | Hypoallergenic: Yes | Size: Fits mattresses up to 15 inches deep

What we like:

  • Oeko-Tex certified 
  • 5-year warranty 
  • 100-night sleep trial

Worth noting:

  • Do not bleach

Why we chose it: Try this value pick from one of our favorite pillow brands for 100 days.

Bye-bye, plasticky covers of yore. Say hello to soft, comfy, and budget-friendly with the most affordable waterproof mattress protector on our list. This one will feel like it’s not even there—and you’ll get a sound night’s sleep knowing your mattress is guarded from spills and so much more. It’s Oeko-Tex certified, meaning it has been tested in a lab against more than 350 harmful substances, and since sleep is one of the most important practices, we consider this a huge plus. Still not sure? Coop Home Goods offers a 100-night sleep trial, which gives you roughly three months to see if it’s a match before you keep it.

Best Organic: Avocado Waterproof Mattress Protector

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Cover material: Organic cotton | Hypoallergenic: Yes | Size: Fits mattresses up to 16 inches deep 

What we like:

  • Limited lifetime warranty
  • Made Safe certified
  • GOTS organic certified cotton

Worth noting:

  • Contains 5% polyurethane, but within GOTS standard for an essential material 

Why we chose it: If you’re all in on organic and natural, this is the protector for you.

This ultrathin waterproof mattress protector is sandwiched between two cozy layers of certified organic cotton, plus it’s Made Safe certified, America’s seal of approval for nontoxic, everyday products (not to mention certified vegan and Greenguard Gold certified). And if the use of polyurethane puts you off, there’s no need to be concerned: It’s within Global Organic Textile Standard (GOTS) guidelines for an essential material accessory. Choose between a standard or deep-pocket size, but be sure to wash whichever one you choose before first use; the cotton used will likely shrink. 

Best Noiseless Protection: Nectar Mattress Protector

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Cover material: Cotton and Tencel | Hypoallergenic: N/A | Size: Fits mattresses up to 22 inches 

What we like:

  • Stain resistant 
  • Quilted top layer
  • 5-year warranty 

Worth noting:

  • That quilted top layer is thick

Why we chose it: Take breakfast in bed—without the noise. 

A mattress protector that’s 100 percent waterproof and stain resistant, all while adding a plush topper to your bed? Yes, please. Nectar balances both form and function in this product—to start, the whole thing slips on and fits snugly on mattresses up to 22 inches (!). The noiseless protector is covered in natural, cooling Tencel fiber, and it’s extra-comfortable thanks to that quilted top layer. It’s ideal for households with busy kids and pets; just toss it in the wash when accidents happen. The five-year warranty isn’t anything to sneeze at, and a 50-night trial period lets you really test it out.

Best Temperature Regulating: Sumbercloud Core Mattress Protector 

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Cover material: HDPE/polyester blend and Tencel | Hypoallergenic: Yes | Size: Fits mattresses up to 16 inches 

What we like:

  • 60-night sleep trial
  • Outlast fabric absorbs and releases heat to regulate body temperature
  • Tencel cover

Worth noting:

  • Pricey

Why we chose it: All you need to know is: NASA-approved. 

If you sleep hot on a regular basis, this mattress protector is about to rock your world—and just in time for peak summer heat. Slumbercloud’s core protector is made with NASA-approved temperature-regulating tech that promises to cool you down while also allowing your mattress to stand up to daily wear and tear and grime. You won’t even notice the barely there Outlast layer tucked into the fold, actively absorbing, storing, releasing, and spreading excess heat so you don’t get hot and bothered. Buyers have boldly stated this protector works better than a cooling bed itself, and at a fraction of the cost.

How We Chose These Products

Mattress protectors, as we previously noted, are not the accessory most people are psyched to dive into—but a good night’s sleep is worth the time investment. Because once you decide on the ideal mattress, it’s time to wrap it up. At Domino, we strive to prioritize bedding brands that balance style, high-quality manufacturing, and eco-conscious attributes. Our editors and writers conduct hands-on testing when possible, and we tap industry experts for their input, dig into brand stats, and conduct independent research. When it comes to the best waterproof mattress protectors, materials, customer reviews, warranties, and comfort level topped our list of features to consider. We also tapped Logan Foley, sleep science coach and managing editor at SleepFoundation.org, for intel.

Our Shopping Checklist

Material 

Materials vary across waterproof mattress protectors, so it’s important to read labels just as you would for clothing. Depending on your preference, there’s a fabric for that. One commonality: polyurethane. While synthetic, this material adds to waterproof ability. While some products, like Avocado’s, use organic cotton, many protectors use Tencel (a plant-based material derived from eucalyptus) for its naturally cooling effect. Others on our list use rayon or polyester.

Waterproofing

A waterproof mattress protector goes above and beyond normal mattress protection. It involves a waterproof material, often polyurethane, which acts as a moisture barrier between the bed and a person. Waterproofing has, historically, created a crunchy-sounding element related to the synthetic materials used—this aspect of construction is something brands today continue to refine and focus on minimizing. 

Care

Most mattress protectors can be easily removed and tossed in a washer and dryer for laundering. This helps to deeply clean and dry while removing bacteria and allergens from the fabric. It’s recommended to wash a protector every two months, unless a big spill occurs—then wash accordingly.

Ask Domino

Q: Do you need a mattress protector if the mattress is waterproof?

While a waterproof mattress may fight against water damage, a mattress protector is essential when it comes to avoiding other stains and damage, says Foley. Be sure to study up on both your mattress and the protector. “Many mattress warranty or trial policies require the use of a mattress protector in order to avoid damage,” he adds. 

Q: Can you use a sheet as a mattress protector?

A sheet’s purpose is to keep you covered and temperature regulated, but it does not offer the same benefits as a protector. Nowadays there are many different protectors based on a person’s sleep preference and general needs. “A big difference between sheets and a mattress protector is the waterproof element of a mattress protector,” Foley notes. “This feature helps prevent issues like mold or mildew,” he adds, exactly what you want to keep away from a mattress.  

Q: What is the difference between a mattress protector and a mattress cover?

A mattress cover or topper doesn’t offer full protection and slides on only the top part of the mattress. Sure, it might prevent a spill from sinking through, but in the long run it won’t protect against mildew and everyday wear and tear. “Essentially every mattress protector is designed with waterproof capabilities.” Foley says. “Mattress protectors are also easily removed and washed, shielding the bed from allergens, dirt, and damage while also making it easier to maintain a clean and fresh sleep surface.”

The Last Word

While mattress protectors may seem like an afterthought, we prefer to think of them as an easy trick to prolonging the life of your mattress—say, an anti-aging serum but for your bed. If you’re still torn and not sure where to start, the Casper Waterproof Mattress Protector is a no-brainer, but we’re also here for the Coop Ultra Luxe Waterproof Mattress Protector, which comes in at even less. 

Domino’s editors independently curate every product on our site, because we’re just as obsessed with a great deal and an under-the-radar discovery as you are. Items you purchase may earn us an affiliate commission.