Hepburn bought the Spanish-style home when she first came to Hollywood in the 1930s.
The super-secluded canyon estate sits on 4,984 square feet and was originally built in 1927.
The light-filled spread offers five bedrooms and five-and-a-half bath as well as several fireplaces—both indoors and out of doors—a heated pool, and a pizza oven in the courtyard.
The master suite boasts its own lounge seating area, a spa-inspired master bathroom, and French doors that open into the scenic outdoors.
A breakfast nook complete with a wooden bar and benches can be found inside the colorfully tiled full cook’s kitchen.
The landscaped backyard includes a rose garden rumored to have been planted by horror-film star Boris Karloff (who owned the home after Hepburn) in the 1940s.